Granulocyte Colony-Stimulating Factor

A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

Also Known As:

G-CSF; Colony Stimulating Factor, Granulocyte; Factor, Granulocyte Colony-Stimulating; Factor, Myeloid Growth; Granulocyte Colony Stimulating Factor; Growth Factor, Myeloid; Colony-Stimulating Factor, Granulocyte; Myeloid Growth Factor

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Colony-Stimulating Factors: 1607
      - Granulocyte Colony-Stimulating Factor: 10186
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1607
        Granulocyte Colony-Stimulating Factor: 10186
  - Glycoproteins: 25180
    - Colony-Stimulating Factors: 1607
      - Granulocyte Colony-Stimulating Factor: 10186
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1607
        Granulocyte Colony-Stimulating Factor: 10186
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Cytokines: 168239
    - Hematopoietic Cell Growth Factors: 13
      - Colony-Stimulating Factors: 1607
        Granulocyte Colony-Stimulating Factor: 10186

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Jonathan R Salisbury Research Topics

Disease

Drug/Important Bio-Agent (IBA)